Go back  Aspartate Transcarbamoylase:  ATCase - (r2)3(c3)2 Reload
regulatory
(r) subunits
 -/+ CTP
 
catalytic
(c) subunits
+/- PALA
 
  "catalytic loops" 230-245 (yellow)
(c
r2c) + 4 PALA / + 2 CTP 
 

c3 + / -  3 PALA 
 

surface catalytic sites  
c3 + / -  3 PALA 
 
 (R) /(T)
"Relaxed" (R) Conformation
 catalytic (c) subunits + PALA ( transition state analog)
"Tense" (T) Conformation
regulatory
(r) subunits + CTP (negative regulatory inhibitor)
@ Duane Sears
December 06, 2008